specific wavelength of ultraviolet (UV) light is not only extremely effective at killing the virus which causes COVID-19, but is also safer for use in public spaces, finds new University of Colorado Boulder research.
The study, published this month in Applied and Environmental Microbiology, is the first to comprehensively analyze the effects of different wavelengths of UV light on SARS-CoV-2 and other respiratory viruses, including the only wavelength safer for living beings to be exposed to without protection.
The findings, which the authors refer to as a "game changer" for UV light use, could lead to new affordable, safe and highly effective systems for reducing viral spread in crowded public spaces like airports and concert venues.
"Of almost every pathogen we have ever studied, this virus is one of the easiest, by far, to kill with UV light," said senior author Karl Linden, professor of environmental engineering. "It takes a very low dose. This indicates that UV technology could be a really good solution for protecting public spaces."
Lumina UV este emisă în mod natural de soare, iar majoritatea formelor sunt dăunătoare ființelor vii --, precum și microorganismelor, cum ar fi virușii. Această lumină poate fi absorbită de genomul unui organism, poate face noduri în el și poate împiedica reproducerea acestuia. Cu toate acestea, aceste lungimi de undă dăunătoare de la soare sunt filtrate de stratul de ozon înainte de a ajunge la suprafața Pământului.
Unele produse obișnuite, cum ar fi lămpile cu tub fluorescent, folosesc lumină UV-de inginerie umană, dar un strat alb de fosfor pe interior protejează oamenii de razele UV.
"When we take that coating off, we can emit those wavelengths, and they can be harmful for our skin and our eyes -- but they can also kill pathogens," said Linden.
Spitalele folosesc deja tehnologia cu lumină UV pentru a dezinfecta suprafețele din spațiile în care nu sunt oameni în ele, utilizând roboți care pot străluci lumina UV în camerele de operație și de pacienți între utilizări.
And many gadgets on the market today clean everything from cell phones to water bottles with UV light. But safety protocols are still being developed by the FDA and EPA. Linden cautions against using any personal or "germicidal" devices in which a person is exposed to UV light.
Noile descoperiri sunt unice, a spus el, deoarece ating punctul favorabil dintre lumina UV, care este relativ sigură pentru oameni și dăunătoare pentru viruși, în special pentru cel care provoacă COVID-19.
"This can be a game changer for the public use of UV light in indoor spaces," said Linden.
Moarte prin expunere
Pentru studiu, Linden și echipa sa au comparat diferite lungimi de undă UV una lângă alta, folosind metode standardizate dezvoltate în industria luminii UV.
"We thought, let's come together and make a definitive statement on what UV exposure is required to kill off SARS-CoV-2," said Linden. "We wanted to make sure that if UV light is being used to control disease, you're delivering the right dose that's protective of human health and human skin, but also going to be killing off these pathogens."
The opportunity to do this kind of work is rare, as there are extremely rigorous safety standards required to work with SARS-CoV-2. So Linden and Ben Ma, postdoctoral researcher in Linden's research group, collaborated with virologist Charles Gerba at the University of Arizona, at a lab cleared to work with the virus and its variants.
The researchers found that while the virus was quite susceptible to UV light in general, a specific wavelength of Far ultraviolet-C, at 222 nanometers, was particularly effective. Created by what's known as a krypton chloride excimer lamp, fueled by molecules moving between different states of energy, this wavelength is very high energy. Therefore, it's able to inflict greater viral protein and nucleic acid damage to the virus compared to other UV-C devices, as well as be blocked by the very top layers of human skin and eyes -- meaning that it has limited to no detrimental health effects at doses that are capable of killing off viruses.
"Not only is it safe, it's also the most effective," said Linden.
Rolul dezinfectării UV astăzi
UV light in various forms has been used widely since the early 20th century to disinfect water, air and surfaces. As early as the 1940s, it was used to reduce the transmission of tuberculosis in hospitals and classrooms, by shining the light at the ceiling to disinfect air as it circulated throughout the room. Today, it's used not only in hospitals, but in some public bathrooms and airplanes when there are no people in those spaces.
In a recent White Paper published by the International UV Association, "Far UV-C Radiation: Current State-of Knowledge," which accompanies the new study, Linden and co-authors argue that this safer wavelength of Far UV-C light could serve as a key mitigation measure against the current and future pandemics, in addition to improved ventilation, mask wearing and vaccination.
Linden își imaginează sisteme care ar putea fie pornirea și oprirea în spații interioare pentru a curăța în mod obișnuit aerul și suprafețele, fie să creeze o barieră continuă, invizibilă, între profesori și studenți, clienți și lucrători din servicii și oameni din spațiile în care distanțarea socială nu este posibilă, pentru a dezinfectează aerul.
UV light disinfection can even rival the positive effects of improved indoor ventilation by providing the equivalent protection of increased air changes per hour within a room. It's also much cheaper to install UV lights than to upgrade an entire HVAC system.
"There is an opportunity here to save money and energy while protecting public health in the same way. It's really exciting," said Linden.
Alți autori ai acestei publicații includ: Ben Ma de la CU Boulder; Patricia Gundy și Charles Gerba de la Universitatea din Arizona; și Mark Sobsey de la Universitatea din Carolina de Nord, Chapel Hill.
